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TUDCA and NAC Supplements to Boost Liver Health

TUDCA and NAC Supplements to Boost Liver Health

TUDCA and NAC have been rising in popularity as supplements recently, and it’s no secret as to why. They both can be extremely effective in boosting liver health, especially when working together. 

But are these supplements right for you? Let’s take a look at what they are, what they do, and what their benefits are. 

What is TUDCA?

TUDCA, or Tauroursodeoxycholic acid, is a bile salt that’s naturally found in our body.  It’s highly soluble in water and is primarily known for its effectiveness in treating cholestasis.

What Is TUDCA Used For?

TUDCA is well-known as a treatment for cholestasis, which is a condition that’s characterized by liver bile acid backup. TUDCA is excellent for this because water-soluble bile acids neutralize the toxicity of regular bile acids in our bodies. 

It also helps as a prevention method for avoiding harmful bile acid from accumulating in the liver, which can damage our cells and membranes. 

Benefits of TUDCA

Though treating cholestasis is a primary use for TUDCA, it has a variety of benefits, many having to do with your liver. 

Reduces Stress in Body Cells

TUDCA protects cells from ER stress by regulating the binding of GRP78 to PERK.

Safeguards Liver From Potential Complications

TUDCA supports healthy bile flow, which assists in detoxification and digestion. This reduces the risk of liver diseases. 

Rehabilitates Your Liver

Tudca enhances bile salt production, which assists in easing liver inflammation and improving liver function. 

Lowers Cholesterol Levels

TUDCA reduces the absorption of cholesterol in the small intestine, which reduces the body’s intake of dietary cholesterol. This lowers the body’s cholesterol content. 

Recommended Dosage of TUDCA Per Day

When taking TUDCA supplements, it’s best to consult your doctor for advice on your dosage. However, there are some common dosage suggestions. 

For Muscle and Liver Insulin Sensitivity

For muscle and liver insulin sensitivity, benefits have been seen at 1,750mg daily, which is the highest dose used for the treatment of fatty liver disease. 

For Improvement in Liver Regenesis Rates

For improvement in liver regenesis rates, the typical recommended dosage is around 10-13 mg daily. 

For Improvement in Bile Salt Composition

For improvement in bile salt composition, the typical recommended dosage is around 15-20 mg daily. 

What is NAC?

NAC, or N-Acetyl Cysteine, is the supplement form of Cysteine, which is a semi-essential amino acid. NAC is not naturally occurring in the body or in food, but it can play an important role in forming glutathione, which is a potent antioxidant. It does this by bonding glutamine with glycine. 

Benefits of NAC

There is a vast list of benefits that NAC supplements offer. 

Produces Glutathione

NAC is valued highly for its antioxidant production. It’s essential to produce and replenish glutathione, as well as glutamine and glycine. 

Glutathione is a vital antioxidant in your body as it helps neutralize free radicals that can damage tissues and cells. 

Antioxidants, in general, help support the body’s immune system and processes for toxin-elimination. There’s also been research that suggests they can reduce the risk of cardiovascular disease. 

Enhances Immunological Functions

The glutathione that NAC produces may benefit immune health, as a deficiency in glutathione can cause certain immune issues. 

Cleanses Your Kidneys and Liver

NAC is an essential aspect of your body’s detoxification process. It helps to prevent side effects of environmental toxin exposure. 

NAC is even given to people who overdose on acetaminophen to prevent or reduce kidney and liver damage. 

Eases Respiratory Conditions

NAC helps to ease symptoms of respiratory issues by loosening and thinning the mucus in your air passageways, acting as both an antioxidant and expectorant. 

It can help with the symptoms of a variety of conditions. 

Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease, or COPD, is a group of diseases that cause airflow blockage and breathing-related problems.


Bronchitis is characterized by inflammation of the lining in your bronchial tubes that carry air to and from your lungs. 

Cystic Fibrosis

Cystic fibrosis is a genetic disorder that can cause severe damage to the lungs and digestive system. 


Asthma is a chronic condition in which your airways narrow, swell, and may produce extra mucus. 

Pulmonary Fibrosis

Pulmonary fibrosis is a lifelong lung disease that causes scarring on the lungs, which thickens over time and makes it harder to breathe. 


Allergies are when your immune system reacts to a foreign substance that is generally harmless to most people. This can cause the lining of the passages in your lungs to swell and make it difficult to breathe. 

Improves Cognitive Performance

Because NAC can replenish and regulate grain glutamate levels, it can help boost brain health and improve cognitive function. 

The neurotransmitter glutamate is vital to a broad range of learning, behavior, and memory functions, while the antioxidant glutathione helps reduce brain cell oxidative damage that is associated with aging. 

It may also have benefits for people with health conditions that affect the brain and memory, like Alzheimer’s disease and Parkinson’s disease.

Enhances Fertility

NAC has been shown to improve both male and female fertility, though it is more prevalent in males. 

Many male fertility issues are exacerbated by antioxidant levels being insufficient to address free radical formation in the reproductive system. Because NAC helps produce antioxidants, it eases these issues. 

NAC may also improve fertility in older women and those with polycystic ovary syndrome by inducing or augmenting the ovulation cycle. 

Stabilizes Blood Sugar Levels

High blood sugar can contribute to inflammation in fat tissue, which can damage or destroy insulin receptors and increase the risk of type 2 diabetes. 

NAC may stabilize blood sugar by decreasing inflammation in fat cells and improving insulin resistance. 

When insulin receptors are healthy, they remove blood sugar from your blood, keeping blood sugar levels within the recommended limits. 

Reduces The Risk of Heart Disease

Oxidative damage in the heart issue can lead to bread disease, strokes, heart attacks, and other severe conditions. NAC may help reduce the risk of heart disease by reducing oxidative damage to the tissues in your heart. 

How TUDCA and NAC Work Together for Liver Support

Enhanced liver support can be provided when TUDCA and NAC are combined. NAC aids in the production of the powerful antioxidant glutathione, while TUDCA neutralizes toxic bile acids. Both are known to promote liver health and protection and can provide even more when they are partnered together. 

TUDCA and NAC Supplements On Nutrition Faktory

Don’t hesitate when it comes to your liver health, whether you need to rehabilitate it or prevent any complications. You can ensure that you’re finding the very highest quality TUDCA and NAC supplements when you shop at Nutrition Faktory

Shop of top picks available in store or online at Nutrition Faktory

Allmax Nutrition TUDCA
Price: Sale price $44.99 (Regular price $59.99)
Description: Tauroursodeoxycholic acid (TUDCA) is a naturally occurring bile derivative known for its liver detoxification properties. It has been traditionally used in Chinese medicine to treat various conditions including liver issues, fever, spasms, and vision problems.

Self Evolve TUDCA

Price: Sale price $49.99 (Regular price $59.99)
Description: TUDCA is a potent liver supplement known for its detoxifying properties. It has been used for thousands of years for various health benefits, including liver detoxification, eye, kidney, and heart health. This product offers 500mg per capsule, double the amount found in many other products.

Titan Nutrition NAC 250srv

Price: Sale price $22.99 (Regular price $29.99)

Allmax Nutrition NAC

Price: Sale price $14.99 (Regular price $21.99)

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